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SARS research
pinpoints Protein M
PLA Daily 2003-06-04
Experts at the Radioactive Medicine Institute
of the Military Academy of Medical Science made a breakthrough
in proteome research of the SARS (severe acute respiratory syndrome)
virus recently.
Led by Academician He Fuchu, director of the
Radioactive Medicine Institute, researchers carried out a large-scale
research on identification of natural structured proteins (protein
M is not yet identified in the world), trying to pinpoint the
pathogenesis of SARS virus so as to provide solid scientific basis
for the diagnosis, treatment and prevention of SARS virus disease.
On the basis of mapping out the molecular structure
of the SARS virus, researchers have discovered three antigen proteins,
found out the molecular structure of virus serum (antibody) and
defined the process of the SARS virus' attack on the Vero clone.
In addition, researchers also discovered for the first time the
strong interaction between furcella protein and nuceocapsid protein.
"The proteome research on the SARS virus will
facilitate a systematic research on pathogenesis of other types
of coronaviruses," the academician explained, "therefore this
research is to provide a technological platform for the research
of other unknown viruses in the future."
By Zhang Feng and Wu Zhijun
(June 4, PLA Daily)
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